Innate Immunity in Diseases of Lung, Heart and Blood: The Idea behind the UA/BWH PGA

Table of Contents

Innate Immunity in Diseases of Lung, Heart and Blood: The Idea behind the UA/BWH PGA

How Immunity Evolved

How the Innate and Adaptive Immune Systems Recognize Pathogens

The Adaptive Immune System

The Cross-talk between Innate and Adaptive Immunity

PPT Slide

How Few Receptors Can Recognize Many Pathogens

Receptors and Targets of Innate Recognition

Innate Discrimination between Self and Non-self is Perfect

Pathogen-Associated Molecular Patterns (PAMPs)

The Pattern Recognition Receptor System of Innate Immunity

TLRs: Not that non-specific...

Pathogen Recognition and the Control of Adaptive Immunity

Costimulation, the Link between Innate and Adaptive Immunity

Innate Immunity Provides Cues for the Adaptive Response

Innate and Adaptive Immunity

The UA/BWH PGA

Immunity at the Host/Environment Interface

PPT Slide

Macrophages Neutrophils (CD14-positive)

Endothelium (CD14-negative)

Epithelium (CD14-negative)

Receptor/Ligand Pairs on Effector Cells

Where Should We Start?

Email: donata@resp-sci.arizona.edu

Home Page: innateimmunity.net

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"Innate Immunity in Diseases of Lung, Heart and Blood: The Idea behind the UA/BWH PGA",Innate Immunity PGA, NHLBI Program in Genomic Applications.. URL http://innateimmunity.net Feb 9, 2001.