Analytical Strategy

• Sequence Data

  • Haplotyping (Gibbs sampling, exact maximum likelihood)
  • Pairwise linkage disequilibrium analysis (likelihood based simulation)
  • Rational choice of SNPs to genotype

• Genotype Data

  • Descriptive analysis (HWE, disequilibrium)
  • Case-control analysis
  • Multi-locus analysis (Malecot models)
  • Haplotyping

Notes: