Innate Immunity in Heart, Lung and Blood Disease
Programs for Genomic Applications
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European-American Asthma 09:42 Thursday, February 5, 2004 30
SNP = CCR4_6067
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Control | 681 | 315 | 996
| 34.39 | 15.91 | 50.30
---------+--------+--------+
Case | 686 | 298 | 984
| 34.65 | 15.05 | 49.70
---------+--------+--------+
Total 1367 613 1980
69.04 30.96 100.00
Frequency Missing = 68
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.4170 0.5184
Likelihood Ratio Chi-Square 1 0.4171 0.5184
Continuity Adj. Chi-Square 1 0.3566 0.5504
Mantel-Haenszel Chi-Square 1 0.4168 0.5185
Phi Coefficient -0.0145
Contingency Coefficient 0.0145
Cramer's V -0.0145
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 681
Left-sided Pr <= F 0.2752
Right-sided Pr >= F 0.7563
Table Probability (P) 0.0315
Two-sided Pr <= P 0.5277
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 0.9391 0.7762 1.1363
Cohort (Col1 Risk) 0.9808 0.9246 1.0403
Cohort (Col2 Risk) 1.0443 0.9155 1.1912
Effective Sample Size = 1980
Frequency Missing = 68
European-American Asthma 09:42 Thursday, February 5, 2004 31
SNP = CCR4_6067
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |2 |4 | Total
---------+--------+--------+
Control | 447 | 51 | 498
| 45.15 | 5.15 | 50.30
---------+--------+--------+
Case | 437 | 55 | 492
| 44.14 | 5.56 | 49.70
---------+--------+--------+
Total 884 106 990
89.29 10.71 100.00
Frequency Missing = 34
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 0.2277 0.6332
Likelihood Ratio Chi-Square 1 0.2277 0.6332
Continuity Adj. Chi-Square 1 0.1402 0.7081
Mantel-Haenszel Chi-Square 1 0.2275 0.6334
Phi Coefficient 0.0152
Contingency Coefficient 0.0152
Cramer's V 0.0152
Pearson Chi-Square Test
----------------------------------
Chi-Square 0.2277
DF 1
Asymptotic Pr > ChiSq 0.6332
Exact Pr >= ChiSq 0.6813
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 447
Left-sided Pr <= F 0.7190
Right-sided Pr >= F 0.3541
Table Probability (P) 0.0731
Two-sided Pr <= P 0.6813
European-American Asthma 09:42 Thursday, February 5, 2004 32
SNP = CCR4_6067
The FREQ Procedure
Statistics for Table of Allele Frequency
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.1031 0.7371 1.6509
Cohort (Col1 Risk) 1.0106 0.9679 1.0551
Cohort (Col2 Risk) 0.9161 0.6391 1.3132
Odds Ratio (Case-Control Study)
-----------------------------------
Odds Ratio 1.1031
Asymptotic Conf Limits
95% Lower Conf Limit 0.7371
95% Upper Conf Limit 1.6509
Exact Conf Limits
95% Lower Conf Limit 0.7222
95% Upper Conf Limit 1.6872
Effective Sample Size = 990
Frequency Missing = 34
European-American Asthma 09:42 Thursday, February 5, 2004 33
SNP = CCR4_6648
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |C |T | Total
---------+--------+--------+
Control | 878 | 68 | 946
| 47.05 | 3.64 | 50.70
---------+--------+--------+
Case | 838 | 82 | 920
| 44.91 | 4.39 | 49.30
---------+--------+--------+
Total 1716 150 1866
91.96 8.04 100.00
Frequency Missing = 182
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 1.8772 0.1707
Likelihood Ratio Chi-Square 1 1.8788 0.1705
Continuity Adj. Chi-Square 1 1.6511 0.1988
Mantel-Haenszel Chi-Square 1 1.8762 0.1708
Phi Coefficient 0.0317
Contingency Coefficient 0.0317
Cramer's V 0.0317
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 878
Left-sided Pr <= F 0.9273
Right-sided Pr >= F 0.0994
Table Probability (P) 0.0266
Two-sided Pr <= P 0.1742
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.2634 0.9037 1.7664
Cohort (Col1 Risk) 1.0189 0.9919 1.0467
Cohort (Col2 Risk) 0.8065 0.5925 1.0978
Effective Sample Size = 1866
Frequency Missing = 182
European-American Asthma 09:42 Thursday, February 5, 2004 34
SNP = CCR4_6648
The FREQ Procedure
Table of Allele Frequency
Allele Frequency
Frequency|
Percent |2 |4 | Total
---------+--------+--------+
Control | 406 | 67 | 473
| 43.52 | 7.18 | 50.70
---------+--------+--------+
Case | 382 | 78 | 460
| 40.94 | 8.36 | 49.30
---------+--------+--------+
Total 788 145 933
84.46 15.54 100.00
Frequency Missing = 91
Statistics for Table of Allele Frequency
Statistic DF Value Prob
------------------------------------------------------
Chi-Square 1 1.3846 0.2393
Likelihood Ratio Chi-Square 1 1.3852 0.2392
Continuity Adj. Chi-Square 1 1.1801 0.2773
Mantel-Haenszel Chi-Square 1 1.3831 0.2396
Phi Coefficient 0.0385
Contingency Coefficient 0.0385
Cramer's V 0.0385
Pearson Chi-Square Test
----------------------------------
Chi-Square 1.3846
DF 1
Asymptotic Pr > ChiSq 0.2393
Exact Pr >= ChiSq 0.2418
Fisher's Exact Test
----------------------------------
Cell (1,1) Frequency (F) 406
Left-sided Pr <= F 0.8975
Right-sided Pr >= F 0.1387
Table Probability (P) 0.0361
Two-sided Pr <= P 0.2418
European-American Asthma 09:42 Thursday, February 5, 2004 35
SNP = CCR4_6648
The FREQ Procedure
Statistics for Table of Allele Frequency
Estimates of the Relative Risk (Row1/Row2)
Type of Study Value 95% Confidence Limits
-----------------------------------------------------------------
Case-Control (Odds Ratio) 1.2373 0.8675 1.7648
Cohort (Col1 Risk) 1.0336 0.9781 1.0923
Cohort (Col2 Risk) 0.8354 0.6187 1.1278
Odds Ratio (Case-Control Study)
-----------------------------------
Odds Ratio 1.2373
Asymptotic Conf Limits
95% Lower Conf Limit 0.8675
95% Upper Conf Limit 1.7648
Exact Conf Limits
95% Lower Conf Limit 0.8542
95% Upper Conf Limit 1.7951
Effective Sample Size = 933
Frequency Missing = 91