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Table of contents

Molecular Genetics Primer

Outline

Nucleotides – The building blocks

Complementary Nucleotides and the Double Helix

Amino acids and polypeptides

Central Dogma of Molecular Biology

Slide 7

SNPs: Functional Anatomy

Base Substitutions

3 Base Codon

Sickle Cell Anemia

Splice Mutations

Deletions

Deletions - microdeletions

Insertions

Myotonic Dystrophy

Repetitive Elements and Anticipation

PowerPoint Presentation

Genome diversification: Meiosis

Errors in Mitosis and Meiosis – the basis of inherited disease

Slide 21

Gene Fusions

Macrodeletions and Duplications due to recombination errors

Slide 24

SNP: Functional Ranking

Author: Benjamin Raby, M.D., F.R.C.P.C.

Homepage: https://innateimmunity.net/

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