Molecular Genetics Primer

Outline

Nucleotides – The building blocks

Complementary Nucleotides and the Double Helix

Amino acids and polypeptides

Central Dogma of Molecular Biology

Central Dogma of Molecular Biology

SNPs: Functional Anatomy

Base Substitutions

3 Base Codon

Sickle Cell Anemia

Splice Mutations

Deletions

Deletions - microdeletions

Insertions

Myotonic Dystrophy

Repetitive Elements and Anticipation

PowerPoint Presentation

Genome diversification: Meiosis

Errors in Mitosis and Meiosis – the basis of inherited disease

Errors in Mitosis and Meiosis – the basis of inherited disease

Gene Fusions

Macrodeletions and Duplications due to recombination errors

Slide 24

SNP: Functional Ranking